Co-regulatory expression quantitative trait loci mapping: method and application to endometrial cancer
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چکیده
منابع مشابه
Quantitative trait loci mapping of panicle traits in rice
In this study 90 individuals of recombinant inbred lines (RILs) were developed by crossing subspecies of japonica rice cultivar, ‘Nagdong’ and an indica type cultivar, ‘Cheongcheong’. These individuals were used to identify the quantitative trait loci of panicle traits using SSR markers. A genetic linkage map was constructed using one hundred fifty four simple sequence repeat ...
متن کاملQuantitative trait loci mapping of panicle traits in rice
In this study 90 individuals of recombinant inbred lines (RILs) were developed by crossing subspecies of japonica rice cultivar, ‘Nagdong’ and an indica type cultivar, ‘Cheongcheong’. These individuals were used to identify the quantitative trait loci of panicle traits using SSR markers. A genetic linkage map was constructed using one hundred fifty four simple sequence repeat ...
متن کاملMapping quantitative trait loci for expression abundance.
Mendelian loci that control the expression levels of transcripts are called expression quantitative trait loci (eQTL). When mapping eQTL, we often deal with thousands of expression traits simultaneously, which complicates the statistical model and data analysis. Two simple approaches may be taken in eQTL analysis: (1) individual transcript analysis in which a single expression trait is mapped a...
متن کاملQuantitative Trait Loci Mapping
With the increasing number of polymorphic markers identified on the genetic map, positional cloning has become an extremely powerful tool, permitting the linkage and identification of a large number of disease genes. As the human genome project pro gresses and the gene map becomes as dense as the microsatellite polymorphism map, scientists will identify more disease genes through a combination...
متن کاملRapid and robust association mapping of expression quantitative trait loci
We applied a simple and efficient two-step method to analyze a family-based association study of gene expression quantitative trait loci (eQTL) in a mixed model framework. This two-step method produces very similar results to the full mixed model method, with our method being significantly faster than the full model. Using the Genetic Analysis Workshop 15 (GAW15) Problem 1 data, we demonstrated...
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ژورنال
عنوان ژورنال: BMC Medical Genomics
سال: 2011
ISSN: 1755-8794
DOI: 10.1186/1755-8794-4-6